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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NOSTRIN Antibody (Center)   

NOSTRIN Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NOSTRIN Antibody (Center) AP13833c
    NOSTRIN Antibody (Center) (Cat. #AP13833c) western blot analysis in mouse heart tissue and HepG2 cell line lysates (35ug/lane).This demonstrates the NOSTRIN antibody detected the NOSTRIN protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IVI9
Other Accession NP_443178.2, NP_001165103.1, NP_001034813.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57660 Da
Antigen Region 296-325 aa
Additional Information
Gene ID 115677
Other Names Nostrin, BM247 homolog, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, eNOS-trafficking inducer, NOSTRIN
Target/Specificity This NOSTRIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human NOSTRIN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNOSTRIN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Cellular Location Isoform 1: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle Cytoplasm, cytoskeleton. Note=Enriched in selected actin structures
Tissue Location Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over- expressed in placenta from women with pre-eclampsia (at protein level).
Research Areas
Citations (0)

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Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.


Holt, R., et al. Eur. J. Hum. Genet. 18(9):1013-1019(2010)
Maestrini, E., et al. Mol. Psychiatry 15(9):954-968(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Wiesenthal, A., et al. Traffic 10(1):26-34(2009)
Schilling, K., et al. Mol. Biol. Cell 17(9):3870-3880(2006)

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$ 295.00
$ 99.00
Cat# AP13833c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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