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ADAMTS5 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP13847a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13847a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ADAMTS5 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | Q9UNA0 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 101718 Da |
ADAMTS5 Antibody (N-term) - Additional info | |
| Gene ID 11096 | |
| Other Names ADAMTS5; ADAMTS11; ADMP2; A disintegrin and metalloproteinase with thrombospondin motifs 5; A disintegrin and metalloproteinase with thrombospondin motifs 11; ADMP-2; Aggrecanase-2 | |
| Target/Specificity This ADAMTS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human ADAMTS5. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ADAMTS5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ADAMTS5 Antibody (N-term) - Protein Information | |
| Name ADAMTS5 | |
| Synonyms ADAMTS11, ADMP2 | |
| Function Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period | |
| Cellular Location Secreted, extracellular space, extracellular matrix (By similarity) | |
| Tissue Location Expressed at low level in placenta primarily but also detected in heart and brain, cervix, uterus, bladder, esophagus, rib cartilage, chondroblastoma, fibrous tissue and a joint capsule from an arthritic patient | |
ADAMTS5 Antibody (N-term) - Related products
AP13847a: ADAMTS5 Antibody (N-term)
AP7447c: ADAMTS5 Antibody (Center)
RI10124: ADAMTS5 predesign siRNA
ADAMTS5 Antibody (N-term) - Application data
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ADAMTS5 Antibody (N-term) (Cat. #AP13847a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ADAMTS5 antibody detected the ADAMTS5 protein (arrow).
ADAMTS5 Antibody (N-term) - Research Areas
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BACKGROUND
ADAMTS5 cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.