|Application ||WB, E|
|Other Accession||P61294, A6QR46, NP_057661.3|
|Calculated MW||23462 Da|
|Antigen Region||167-195 aa|
|Other Names||Ras-related protein Rab-6B, RAB6B|
|Target/Specificity||This RAB6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-195 amino acids from the C-terminal region of human RAB6B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB6B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.|
|Cellular Location||Golgi apparatus membrane; Lipid- anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle. Note=Colocalizes with BICD1 at vesicular structures that align along microtubules|
|Tissue Location||Predominantly expressed in brain.|
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Provided below are standard protocols that you may find useful for product applications.
RAB6B seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Wanschers, B., et al. Cell Motil. Cytoskeleton 65(3):183-196(2008)
Wanschers, B.F., et al. Exp. Cell Res. 313(16):3408-3420(2007)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Garcia-Saez, I., et al. Acta Crystallogr. D Biol. Crystallogr. 62 (PT 7), 725-733 (2006) :
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