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EDN2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - EDN2 Antibody (C-term) AP13863B
    EDN2 Antibody (C-term) (Cat. #AP13863b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EDN2 antibody detected the EDN2 protein (arrow).
    detail
  • WB - EDN2 Antibody (C-term) AP13863B
    Western blot analysis of EDN2 (arrow) using rabbit polyclonal EDN2 Antibody (C-term) (Cat. #AP13863b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the EDN2 gene.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P20800
Other Accession Q28470, NP_001947.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 19960 Da
Antigen Region 107-136 aa
Additional Information
Gene ID 1907
Other Names Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2
Target/Specificity This EDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the C-terminal region of human EDN2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEDN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EDN2
Function Endothelins are endothelium-derived vasoconstrictor peptides.
Cellular Location Secreted.
Tissue Location Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. [provided by RefSeq].

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Darrah, R., et al. Physiol. Genomics 41(1):71-77(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :
Wiesmann, F., et al. Breast Cancer Res. 11 (3), R34 (2009) :

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$ 182.50
$ 70.00
Cat# AP13863B
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