|Application ||WB, E|
|Other Accession||Q28470, NP_001947.1|
|Calculated MW||19960 Da|
|Antigen Region||107-136 aa|
|Other Names||Endothelin-2, ET-2, Preproendothelin-2, PPET2, EDN2|
|Target/Specificity||This EDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the C-terminal region of human EDN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EDN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Endothelins are endothelium-derived vasoconstrictor peptides.|
|Tissue Location||Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. [provided by RefSeq].
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Darrah, R., et al. Physiol. Genomics 41(1):71-77(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :
Wiesmann, F., et al. Breast Cancer Res. 11 (3), R34 (2009) :
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