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GUCA2A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q02747 |
| Other Accession | NP_291031.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 12388 Da |
| Antigen Region | 25-54 aa |
| Gene ID | 2980 |
|---|---|
| Other Names | Guanylin, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, GCAP-I, HMW-guanylin, Guanylin, GUCA2A, GUCA2 |
| Target/Specificity | This GUCA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human GUCA2A. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GUCA2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GUCA2A |
|---|---|
| Synonyms | GUCA2 |
| Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. |
| Cellular Location | Secreted. |
| Tissue Location | Highly expressed in ileum and colon. Found in plasma |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
References
Dell'Orco, D., et al. Cell. Mol. Life Sci. 67(6):973-984(2010)
Chen, Y.B., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12(5):515-517(2009)
Albano, F., et al. Pediatr. Res. 58(1):159-163(2005)
Sindic, A., et al. Kidney Int. 67(4):1420-1427(2005)
Kulaksiz, H., et al. Gastroenterology 126(3):732-740(2004)
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