|Application ||WB, E|
|Calculated MW||12388 Da|
|Antigen Region||25-54 aa|
|Other Names||Guanylin, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, GCAP-I, HMW-guanylin, Guanylin, GUCA2A, GUCA2|
|Target/Specificity||This GUCA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the Central region of human GUCA2A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GUCA2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.|
|Tissue Location||Highly expressed in ileum and colon. Found in plasma|
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Provided below are standard protocols that you may find useful for product applications.
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
Dell'Orco, D., et al. Cell. Mol. Life Sci. 67(6):973-984(2010)
Chen, Y.B., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12(5):515-517(2009)
Albano, F., et al. Pediatr. Res. 58(1):159-163(2005)
Sindic, A., et al. Kidney Int. 67(4):1420-1427(2005)
Kulaksiz, H., et al. Gastroenterology 126(3):732-740(2004)
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