|Application ||WB, E|
|Calculated MW||64248 Da|
|Antigen Region||517-546 aa|
|Other Names||Mucolipin-3, MCOLN3|
|Target/Specificity||This MCOLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517-546 amino acids from the C-terminal region of human MCOLN3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MCOLN3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Mucolipins constitute a family of cation channel proteins with homologs in mouse, Drosophila, and C. elegans. Mutations in the human MCOLN1 gene (MIM 605248) cause mucolipodosis IV (MIM 262650).
Kim, H.J., et al. J. Biol. Chem. 285(22):16513-16520(2010)
Curcio-Morelli, C., et al. J. Cell. Physiol. 222(2):328-335(2010)
Kim, H.J., et al. Traffic 10(8):1157-1167(2009)
Martina, J.A., et al. Traffic 10(8):1143-1156(2009)
Grimm, C., et al. J. Biol. Chem. 284(20):13823-13831(2009)
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