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DNASE1L3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DNASE1L3 Antibody (N-term) AP13885a
    DNASE1L3 Antibody (N-term) (Cat. #AP13885a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DNASE1L3 antibody detected the DNASE1L3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13609
Other Accession NP_004935.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35504 Da
Antigen Region 14-43 aa
Additional Information
Gene ID 1776
Other Names Deoxyribonuclease gamma, DNase gamma, 3121-, DNase I homolog protein DHP2, Deoxyribonuclease I-like 3, DNase I-like 3, Liver and spleen DNase, LS-DNase, LSD, DNASE1L3, DHP2, DNAS1L3
Target/Specificity This DNASE1L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human DNASE1L3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDNASE1L3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DHP2, DNAS1L3
Function Has DNA hydrolytic activity. Does not bind to actin. Cleaves chromatin DNA to nucleosomal units.
Cellular Location Nucleus. Note=May first pass through the ER membrane before being imported in the nucleus
Tissue Location Liver and spleen.
Research Areas
Citations (0)

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This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ueki, M., et al. Clin. Chim. Acta 407 (1-2), 20-24 (2009) :
Mizuta, R., et al. Biomed. Res. 30(3):165-170(2009)
Boulares, H., et al. Biochem. Biophys. Res. Commun. 341(2):653-662(2006)
Okamoto, M., et al. Biochem. Biophys. Res. Commun. 327(1):76-83(2005)

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Cat# AP13885a
(40 western blots)
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