|Application ||WB, IHC-P, E|
|Calculated MW||57464 Da|
|Antigen Region||446-474 aa|
|Other Names||Serine/threonine-protein kinase Nek3, Never in mitosis A-related kinase 3, NimA-related protein kinase 3, Nek3|
|Target/Specificity||This Mouse Nek3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-474 amino acids from the C-terminal region of mouse Nek3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Nek3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin- mediated phosphorylation of PXN and VAV2.|
|Cellular Location||Cytoplasm. Cell projection, axon|
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Kinase that may play a role in mitotic regulation.
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