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>   home   >   Products   >   Primary Antibodies   >   Mouse Pak3 Antibody (N-term)   

Mouse Pak3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Pak3 Antibody (N-term) AP13931a
    Western blot analysis of lysates from Hela, Jurkat cell line (from left to right), using Mouse Pak3 Antibody (N-term)(Cat. #AP13931a). AP13931a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • WB - Mouse Pak3 Antibody (N-term) AP13931a
    Western blot analysis of lysate from mouse NIH/3T3 cell line, using Mouse Pak3 Antibody (N-term)(Cat. #AP13931a). AP13931a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • IHC-P - Mouse Pak3 Antibody (N-term) AP13931a
    Mouse Pak3 Antibody (N-term) (AP13931a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pak3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q61036
Other Accession Q8AXB4, Q62829, O75914, NP_001181977.1, NP_032804.2
Reactivity Mouse
Predicted Human, Rat, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 62398 Da
Antigen Region 124-152 aa
Additional Information
Gene ID 18481
Other Names Serine/threonine-protein kinase PAK 3, Beta-PAK, CDC42/RAC effector kinase PAK-B, p21-activated kinase 3, PAK-3, Pak3, Pak-3, Pakb, Stk4
Target/Specificity This Mouse Pak3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of mouse Pak3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Pak3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pak3
Synonyms Pak-3, Pakb, Stk4
Function Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.
Cellular Location Cytoplasm.
Citations (0)

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Key regulator of synapse formation and plasticity in the hippocampus.


Shimogori, T., et al. Nat. Neurosci. 13(6):767-775(2010)
Jiang, X.S., et al. Hum. Mol. Genet. 19(7):1347-1357(2010)
Demyanenko, G.P., et al. Neuroscience 165(1):107-115(2010)
Grimsley-Myers, C.M., et al. J. Neurosci. 29(50):15859-15869(2009)
Sansom, S.N., et al. PLoS Genet. 5 (6), E1000511 (2009) :

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$ 295.00
$ 99.00
Cat# AP13931a
(40 western blots)
Availability: In Stock
Bulk Size
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