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ABP1 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP13940a 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP13940a-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
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ABP1 Antibody (N-term) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionP19801
Other AccessionNP_001082.2
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW85378 Da

ABP1 Antibody (N-term) - Additional info

Gene ID 26
Other Names
ABP1; AOC1; DAO1; Amiloride-sensitive amine oxidase [copper-containing]; Amiloride-binding protein; Histaminase; Kidney amine oxidase
Target/Specificity
This ABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 amino acids from the N-terminal region of human ABP1.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
ABP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.

ABP1 Antibody (N-term) - Protein Information

Name ABP1
Synonyms AOC1, DAO1
Function
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis Placental DAO is thought to play a role in the regulation of the female reproductive function
Cellular Location
Secreted, extracellular space.
Tissue Location
Placenta and kidney.

ABP1 Antibody (N-term) - Related products

AP13940a: ABP1 Antibody (N-term)

ABP1 Antibody (N-term) - Application data

  • ABP1 Antibody (N-term) (Cat. #AP13940a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ABP1 antibody detected the ABP1 protein (arrow).

ABP1 Antibody (N-term) - Research Areas

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BACKGROUND

This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

REFERENCES

Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) McGrath, A.P., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 2), 137-142 (2010) : Chambers, J.C., et al. Nat. Genet. 42(2):149-152(2010) McGrath, A.P., et al. Biochemistry 48(41):9810-9822(2009) Song, W.B., et al. World J. Gastroenterol. 15(31):3916-3919(2009)