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ABP1 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP13940a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13940a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ABP1 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | P19801 |
| Other Accession | NP_001082.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 85378 Da |
ABP1 Antibody (N-term) - Additional info | |
| Gene ID 26 | |
| Other Names ABP1; AOC1; DAO1; Amiloride-sensitive amine oxidase [copper-containing]; Amiloride-binding protein; Histaminase; Kidney amine oxidase | |
| Target/Specificity This ABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 amino acids from the N-terminal region of human ABP1. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABP1 Antibody (N-term) - Protein Information | |
| Name ABP1 | |
| Synonyms AOC1, DAO1 | |
| Function Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis Placental DAO is thought to play a role in the regulation of the female reproductive function | |
| Cellular Location Secreted, extracellular space. | |
| Tissue Location Placenta and kidney. | |
ABP1 Antibody (N-term) - Related products
ABP1 Antibody (N-term) - Application data
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ABP1 Antibody (N-term) (Cat. #AP13940a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ABP1 antibody detected the ABP1 protein (arrow).
ABP1 Antibody (N-term) - Research Areas
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BACKGROUND
This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
REFERENCES
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) McGrath, A.P., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 2), 137-142 (2010) : Chambers, J.C., et al. Nat. Genet. 42(2):149-152(2010) McGrath, A.P., et al. Biochemistry 48(41):9810-9822(2009) Song, W.B., et al. World J. Gastroenterol. 15(31):3916-3919(2009)