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DAO Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DAO Antibody (Center) AP13941c
    DAO Antibody (Center) (Cat. #AP13941c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the DAO antibody detected the DAO protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P14920
Other Accession NP_001908.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39474 Da
Antigen Region 259-287 aa
Additional Information
Gene ID 1610
Other Names D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX
Target/Specificity This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human DAO.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDAO Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DAO
Synonyms DAMOX
Function Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Cellular Location Peroxisome.
Research Areas
Citations (0)

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This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.


Kim, B., et al. Psychiatry Res 179(2):121-125(2010)
Caldinelli, L., et al. Protein Sci. 19(8):1500-1512(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Ohnuma, T., et al. Schizophr. Res. 118 (1-3), 300-302 (2010) :
Mitchell, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(16):7556-7561(2010)

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$ 295.00
$ 99.00
Cat# AP13941c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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