|Application ||WB, E|
|Other Accession||Q6SP97, NP_659447.1|
|Calculated MW||29454 Da|
|Antigen Region||109-137 aa|
|Other Names||Enkurin, ENKUR, C10orf63|
|Target/Specificity||This C10orf63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the Central region of human C10orf63.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||C10orf63 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel.|
|Cellular Location||Cell projection, cilium, flagellum. Note=Sperm acrosomal crescent and flagellar principal piece|
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Provided below are standard protocols that you may find useful for product applications.
Enkurin interacts with transient receptor potential canonical (TRPC) cation channels (see TRPC1; MIM 602343) and functions as an adaptor protein, tethering signal transduction proteins to TRPC channels (Sutton et al., 2004 [PubMed 15385169]).
Beech, D.J. Handb Exp Pharmacol 179, 109-123 (2007) :
Sutton, K.A., et al. Dev. Biol. 274(2):426-435(2004)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
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