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ENKUR Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8TC29 |
| Other Accession | Q6SP97, NP_659447.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29454 Da |
| Antigen Region | 109-137 aa |
| Gene ID | 219670 |
|---|---|
| Other Names | Enkurin, ENKUR, C10orf63 |
| Target/Specificity | This ENKUR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the Central region of human ENKUR. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ENKUR Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ENKUR (HGNC:28388) |
|---|---|
| Synonyms | C10orf63 |
| Function | Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel (By similarity). Microtubule inner protein (MIP) part of the dynein- decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q6SP97}. Note=Sperm acrosomal crescent and flagellar principal piece. {ECO:0000250|UniProtKB:Q6SP97} |
| Tissue Location | Expressed in airway epithelial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Enkurin interacts with transient receptor potential canonical (TRPC) cation channels (see TRPC1; MIM 602343) and functions as an adaptor protein, tethering signal transduction proteins to TRPC channels (Sutton et al., 2004 [PubMed 15385169]).
References
Beech, D.J. Handb Exp Pharmacol 179, 109-123 (2007) :
Sutton, K.A., et al. Dev. Biol. 274(2):426-435(2004)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
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