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HIST2H2AA4 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP13961b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP13961b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
HIST2H2AA4 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | Q6FI13 |
| Other Accession | Q4FZT6, Q8BFU2, Q7L7L0, P0CC09, Q6GSS7, P02262, P22752, P0C0S8, P0C0S9, P0C170, P20671, P0C169, Q93077, P04908, NP_003507.1, NP_001035807.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 14095 Da |
HIST2H2AA4 Antibody (C-term) - Additional info | |
| Gene ID 8337 | |
| Other Names HIST2H2AA3; H2AFO; HIST2H2AA; Histone H2A type 2-A; Histone H2A.2; Histone H2A/o | |
| Target/Specificity This HIST2H2AA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the C-terminal region of human HIST2H2AA4. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions HIST2H2AA4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
HIST2H2AA4 Antibody (C-term) - Protein Information | |
| Name HIST2H2AA3 | |
| Synonyms H2AFO, HIST2H2AA | |
| Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling | |
| Cellular Location Nucleus. Chromosome. | |
HIST2H2AA4 Antibody (C-term) - Related products
HIST2H2AA4 Antibody (C-term) - Application data
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HIST2H2AA4 Antibody (C-term) (Cat. #AP13961b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the HIST2H2AA4 antibody detected the HIST2H2AA4 protein (arrow).
HIST2H2AA4 Antibody (C-term) - Research Areas
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BACKGROUND
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
REFERENCES
Braastad, C.D., et al. Gene 342(1):35-40(2004) Marzluff, W.F., et al. Genomics 80(5):487-498(2002) Mannironi, C., et al. DNA Cell Biol. 13(2):161-170(1994) Allen, B.S., et al. Genomics 10(2):486-488(1991)
