|Application ||WB, IHC-P, E|
|Other Accession||NP_004641.1, NP_001135861.1, NP_001166143.1|
|Calculated MW||27980 Da|
|Antigen Region||171-199 aa|
|Other Names||Patatin-like phospholipase domain-containing protein 4, Protein GS2, PNPLA4, DXS1283E, GS2|
|Target/Specificity||This PNPLA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human PNPLA4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PNPLA4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in all tissues examined, including heart, brain, placenta, lung, liver, muscle, kidney, pancreas and spleen.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y.
Gao, J.G., et al. Mol. Genet. Metab. 96(4):253-260(2009)
Kienesberger, P.C., et al. J. Lipid Res. 50 SUPPL, S63-S68 (2009) :
Johansson, L.E., et al. PLoS ONE 4 (4), E5327 (2009) :
Gao, J.G., et al. Biochem. Biophys. Res. Commun. 360(2):501-506(2007)
Wilson, P.A., et al. J. Lipid Res. 47(9):1940-1949(2006)
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