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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PPCDC Antibody (N-term)   

PPCDC Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PPCDC Antibody (N-term) AP13975a
    PPCDC Antibody (N-term) (Cat. #AP13975a) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the PPCDC antibody detected the PPCDC protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q96CD2
Other Accession NP_068595.3
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 22395 Da
Antigen Region 37-66 aa
Additional Information
Gene ID 60490
Other Names Phosphopantothenoylcysteine decarboxylase, PPC-DC, CoaC, PPCDC, COAC
Target/Specificity This PPCDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PPCDC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPPCDC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPCDC
Synonyms COAC
Function Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'- phosphopantotheine.
Research Areas
Citations (0)

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Background

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).

References

Strauss, E., et al. Biochemistry 43(49):15520-15533(2004)
Manoj, N., et al. Acta Crystallogr. D Biol. Crystallogr. 59 (PT 10), 1762-1766 (2003) :
Daugherty, M., et al. J. Biol. Chem. 277(24):21431-21439(2002)

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$ 295.00
$ 99.00
Cat# AP13975a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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