|Application ||WB, IHC-P, E|
|Other Accession||Q8CGY6, NP_001028748.1, NP_775259.1|
|Calculated MW||103733 Da|
|Antigen Region||235-264 aa|
|Other Names||Protein unc-45 homolog B, Unc-45B, SMUNC45, UNC45B, CMYA4, UNC45|
|Target/Specificity||This UNC45B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the N-terminal region of human UNC45B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UNC45B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.|
|Cellular Location||Cytoplasm, cytosol.|
|Tissue Location||Expressed in eye lens tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
UNC45B plays a role in myoblast fusion and sarcomere organization (Price et al., 2002 [PubMed 12356907]).[supplied by OMIM].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Price, M.G., et al. J. Cell. Sci. 115 (PT 21), 4013-4023 (2002) :
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