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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   HEXIM1 Antibody (N-term)   

HEXIM1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HEXIM1 Antibody (N-term) AP13992a
    HEXIM1 Antibody (N-term) (Cat. #AP13992a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow).
  • WB - HEXIM1 Antibody (N-term) AP13992a
    HEXIM1 Antibody (N-term) (Cat. #AP13992a) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the HEXIM1 antibody detected the HEXIM1 protein (arrow).
  • IHC-P - HEXIM1 Antibody (N-term) AP13992a
    HEXIM1 Antibody (N-term) (Cat. #AP13992a)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HEXIM1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94992
Other Accession Q0X0C4, NP_006451.1
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40623 Da
Antigen Region 18-46 aa
Additional Information
Gene ID 10614
Other Names Protein HEXIM1, Cardiac lineage protein 1, Estrogen down-regulated gene 1 protein, Hexamethylene bis-acetamide-inducible protein 1, Menage a quatre protein 1, HEXIM1, CLP1, EDG1, HIS1, MAQ1
Target/Specificity This HEXIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human HEXIM1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHEXIM1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CLP1, EDG1, HIS1, MAQ1
Function Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
Cellular Location Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear
Tissue Location Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed Expressed in endocrine tissues.
Research Areas
Citations (0)

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Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.


Dow, E.C., et al. J. Cell. Physiol. 224(1):84-93(2010)
Ogba, N., et al. Oncogene 29(25):3639-3649(2010)
Schonichen, A., et al. Biochemistry 49(14):3083-3091(2010)
Czudnochowski, N., et al. J. Mol. Biol. 395(1):28-41(2010)
Krueger, B.J., et al. PLoS ONE 5 (8), E12335 (2010) :

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Cat# AP13992a
(40 western blots)
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