|Application ||WB, E|
|Calculated MW||37728 Da|
|Antigen Region||301-330 aa|
|Other Names||Pulmonary surfactant-associated protein D, PSP-D, SP-D, Collectin-7, Lung surfactant protein D, SFTPD, COLEC7, PSPD, SFTP4|
|Target/Specificity||This SFTPD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from the C-terminal region of human SFTPD.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SFTPD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||COLEC7, PSPD, SFTP4|
|Function||Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.|
|Cellular Location||Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film|
|Tissue Location||Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).|
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Provided below are standard protocols that you may find useful for product applications.
SFTPD contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Hartshorn, K.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (3), L384-L392 (2010) :
de Wit, E., et al. Mamm. Genome (2010) In press :
Paantjens, A.W., et al. Transplantation 90(3):340-342(2010)
Barlo, N.P., et al. Sarcoidosis Vasc Diffuse Lung Dis 26(2):155-161(2009)
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