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SSTR1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SSTR1 Antibody (C-term) AP14037b
    SSTR1 Antibody (C-term) (Cat. #AP14037b) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the SSTR1 antibody detected the SSTR1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P30872
Other Accession P28646, P30873, NP_001040.1
Reactivity Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42686 Da
Antigen Region 351-380 aa
Additional Information
Gene ID 6751
Other Names Somatostatin receptor type 1, SS-1-R, SS1-R, SS1R, SRIF-2, SSTR1
Target/Specificity This SSTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from the C-terminal region of human SSTR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSTR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSTR1
Function Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach
Research Areas
Citations (0)
citation

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Background

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach. [provided by RefSeq].

References

Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Pisarek, H., et al. Folia Histochem. Cytobiol. 48(1):142-147(2010)
Johansson, M., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1644-1650(2009)
Casarini, A.P., et al. Pituitary 12(4):297-303(2009)

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$ 182.50
$ 70.00
Cat# AP14037b
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