|Application ||WB, E|
|Other Accession||NP_001095132.1, NP_002516.2|
|Calculated MW||131572 Da|
|Antigen Region||333-361 aa|
|Other Names||Nardilysin, N-arginine dibasic convertase, NRD convertase, NRD-C, NRD1|
|Target/Specificity||This NRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the Central region of human NRD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NRD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.|
|Tissue Location||Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues|
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Provided below are standard protocols that you may find useful for product applications.
NRD1 cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.
Korovkina, V.P., et al. Am. J. Physiol., Cell Physiol. 296 (3), C433-C440 (2009) :
Hiraoka, Y., et al. Biochem. Biophys. Res. Commun. 370(1):154-158(2008)
Bernstein, H.G., et al. Neuroscience 146(4):1513-1523(2007)
Nishi, E., et al. J. Biol. Chem. 281(41):31164-31172(2006)
Hospital, V., et al. Protein Pept. Lett. 11(5):501-508(2004)
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