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TRPV2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TRPV2 Antibody (N-term) AP14049a
    TRPV2 Antibody (N-term) (Cat. #AP14049a) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRPV2 antibody detected the TRPV2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y5S1
Other Accession NP_057197.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 85981 Da
Antigen Region 52-81 aa
Additional Information
Gene ID 51393
Other Names Transient receptor potential cation channel subfamily V member 2, TrpV2, Osm-9-like TRP channel 2, OTRPC2, Vanilloid receptor-like protein 1, VRL-1, TRPV2, VRL
Target/Specificity This TRPV2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human TRPV2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRPV2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRPV2
Synonyms VRL
Function Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasm Melanosome. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Research Areas
Citations (0)

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This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat.


Mercado, J., et al. J. Neurosci. 30(40):13338-13347(2010)
Nabissi, M., et al. Carcinogenesis 31(5):794-803(2010)
Monet, M., et al. Cancer Res. 70(3):1225-1235(2010)
Liu, G., et al. Cancer Genet. Cytogenet. 197(1):54-59(2010)
Saunders, C.I., et al. Biochim. Biophys. Acta 1792(10):1019-1026(2009)

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$ 295.00
$ 99.00
Cat# AP14049a
(40 western blots)
Availability: In Stock
Bulk Size
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