|Application ||WB, IHC-P, E|
|Other Accession||NP_002552.2, NP_778255.1, NP_778256.1|
|Calculated MW||47205 Da|
|Antigen Region||325-353 aa|
|Other Names||P2X purinoceptor 5, P2X5, ATP receptor, Purinergic receptor, P2RX5, P2X5|
|Target/Specificity||This P2RX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-353 amino acids from the C-terminal region of human P2RX5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||P2RX5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for ATP that acts as a ligand-gated ion channel.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed at high levels in brain and immune system|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Three transcript variants encoding distinct isoforms have been identified for this gene.
Kotnis, S., et al. Mol. Pharmacol. 77(6):953-960(2010)
Overes, I.M., et al. Cancer Immunol. Immunother. 58(3):429-439(2009)
Dubyak, G.R. Mol. Pharmacol. 72(6):1402-1405(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Duckwitz, W., et al. J. Biol. Chem. 281(51):39561-39572(2006)
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