|Application ||WB, E|
|Calculated MW||83418 Da|
|Antigen Region||200-228 aa|
|Other Names||Disintegrin and metalloproteinase domain-containing protein 11, ADAM 11, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein, MDC, ADAM11, MDC|
|Target/Specificity||This ADAM11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the N-terminal region of human ADAM11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ADAM11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed predominantly in brain. Slightly detected or not at all in other tissues|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq].
Fu, G.K., et al. Genomics 84(1):205-210(2004)
Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :
Shea, S.H., et al. Behav. Genet. 31(2):231-239(2001)
Sagane, K., et al. Biochem. J. 334 (PT 1), 93-98 (1998) :
Wolfsberg, T.G., et al. J. Cell Biol. 131(2):275-278(1995)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.