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ADAM11 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP14066a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14066a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ADAM11 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | O75078 |
| Other Accession | NP_002381.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 83418 Da |
ADAM11 Antibody (N-term) - Additional info | |
| Gene ID 4185 | |
| Other Names ADAM11; MDC; Disintegrin and metalloproteinase domain-containing protein 11; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein | |
| Target/Specificity This ADAM11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the N-terminal region of human ADAM11. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ADAM11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ADAM11 Antibody (N-term) - Protein Information | |
| Name ADAM11 | |
| Synonyms MDC | |
| Function Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein | |
| Cellular Location Membrane; Single-pass type I membrane protein | |
| Tissue Location Expressed predominantly in brain. Slightly detected or not at all in other tissues | |
ADAM11 Antibody (N-term) - Related products
AP14066a: ADAM11 Antibody (N-term)
ADAM11 Antibody (N-term) - Application data
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ADAM11 Antibody (N-term) (Cat. #AP14066a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ADAM11 antibody detected the ADAM11 protein (arrow).
ADAM11 Antibody (N-term) - Research Areas
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BACKGROUND
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq].
REFERENCES
Fu, G.K., et al. Genomics 84(1):205-210(2004) Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) : Shea, S.H., et al. Behav. Genet. 31(2):231-239(2001) Sagane, K., et al. Biochem. J. 334 (PT 1), 93-98 (1998) : Wolfsberg, T.G., et al. J. Cell Biol. 131(2):275-278(1995)
