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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Npr1 Antibody (N-term)   

Mouse Npr1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Npr1 Antibody (N-term) AP14073A
    Mouse Npr1 Antibody (N-term) (Cat. #AP14073a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Npr1 antibody detected the Npr1 protein (arrow).
  • IHC-P - Mouse Npr1 Antibody (N-term) AP14073A
    Mouse Npr1 Antibody (N-term) (AP14073a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse duodenum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Npr1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P18293
Other Accession NP_032753.5
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 119109 Da
Antigen Region 198-226 aa
Additional Information
Gene ID 18160
Other Names Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A, Npr1, Npra
Target/Specificity This Mouse Npr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the N-terminal region of mouse Npr1.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Npr1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Npr1
Synonyms Npra
Function Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.

References

Madhani, M., et al. Am. J. Physiol. Heart Circ. Physiol. 299 (3), H827-H836 (2010) :
Panayiotou, C.M., et al. Br. J. Pharmacol. 160(8):2045-2054(2010)
Ropero, A.B., et al. Endocrinology 151(8):3665-3674(2010)
Tankersley, C.G., et al. Inhal Toxicol 22(8):695-707(2010)
Long, L., et al. Neuro Endocrinol. Lett. 31(1):126-130(2010)

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Cat# AP14073A
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(40 western blots)
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