|Application ||WB, E|
|Calculated MW||51457 Da|
|Antigen Region||1-30 aa|
|Other Names||Sodium-coupled neutral amino acid transporter 5, Solute carrier family 38 member 5, System N transporter 2, SLC38A5, JM24, SN2, SNAT5|
|Target/Specificity||This SLC38A5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SLC38A5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC38A5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||JM24, SN2, SNAT5|
|Function||Functions as a sodium-dependent amino acid transporter which countertransport protons. Mediates the saturable, pH- sensitive, and electrogenic cotransport of several neutral amino acids including glycine, asparagine, alanine, serine, glutamine and histidine with sodium.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Predominantly expressed in stomach, brain, liver, lung and intestinal tract.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a system N sodium-coupled amino acid transporter involved in the transfer of glutamine, asparagine, histidine, serine, alanine, and glycine. The encoded protein does not transport charged amino acids, imino acids, or N-alkylated amino acids. This transporter is not inhibited by lithium.
Broer, S. Physiol. Rev. 88(1):249-286(2008)
Froyen, G., et al. Hum. Genet. 121(5):539-547(2007)
Nakanishi, T., et al. Biochem. Biophys. Res. Commun. 281(5):1343-1348(2001)
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