|Application ||WB, IHC-P, E|
|Other Accession||P25801, NP_001135788.1, NP_001135787.1, NP_005565.2|
|Calculated MW||18358 Da|
|Antigen Region||1-30 aa|
|Other Names||Rhombotin-2, Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, T-cell translocation protein 2, LMO2, RBTN2, RBTNL1, RHOM2, TTG2|
|Target/Specificity||This LMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LMO2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LMO2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||RBTN2, RBTNL1, RHOM2, TTG2|
|Function||Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
Oram, S.H., et al. Oncogene 29(43):5796-5808(2010)
Younes, S.F., et al. Am. J. Surg. Pathol. 34(9):1266-1276(2010)
Hirose, K., et al. Blood 116(6):962-970(2010)
Durnick, D.K., et al. Am. J. Clin. Pathol. 134(2):278-281(2010)
Cobanoglu, U., et al. Hematology 15(3):132-134(2010)
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