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CCS Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP14113c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14113c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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CCS Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | O14618 |
| Other Accession | Q6PWT7, NP_005116.1 |
| Reactivity | Human |
| Predicted | Pig |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 29041 Da |
CCS Antibody (Center) - Additional info | |
| Gene ID 9973 | |
| Other Names CCS; Copper chaperone for superoxide dismutase; Superoxide dismutase copper chaperone | |
| Target/Specificity This CCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-170 amino acids from the Central region of human CCS. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions CCS Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
CCS Antibody (Center) - Protein Information | |
| Name CCS | |
| Function Delivers copper to copper zinc superoxide dismutase (SOD1) | |
| Cellular Location Cytoplasm. | |
| Tissue Location Ubiquitous. | |
CCS Antibody (Center) - Related products
CCS Antibody (Center) - Application data
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CCS Antibody (Center) (Cat. #AP14113c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CCS antibody detected the CCS protein (arrow).
CCS Antibody (Center) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
REFERENCES
Brady, G.F., et al. Mol. Cell. Biol. 30(8):1923-1936(2010) Winkler, D.D., et al. Biochemistry 48(15):3436-3447(2009) Barry, A.N., et al. Biochemistry 47(49):13074-13083(2008) Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008) Furukawa, Y., et al. J. Biol. Chem. 283(35):24167-24176(2008)