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AES Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP14115b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP14115b-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
  • Citiations : 0
  • Reviews
  • Protocols
  • Backgrounds

AES Antibody (C-term) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ08117
Other AccessionNP_001121.2
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW21970 Da

AES Antibody (C-term) - Additional info

Gene ID 166
Other Names
AES; GRG; Amino-terminal enhancer of split; Gp130-associated protein GAM; Protein ESP1; Protein GRG
Target/Specificity
This AES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-184 amino acids from the C-terminal region of human AES.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
AES Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

AES Antibody (C-term) - Protein Information

Name AES
Synonyms GRG
Function
Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state
Cellular Location
Nucleus (By similarity).
Tissue Location
Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver

AES Antibody (C-term) - Related products

AP14115b: AES Antibody (C-term)

RI10159: AES predesign siRNA

DC09893: Human AES cDNA Clone

LY12278a: AES Over-expression Lysate

AT1063a: AES Antibody (monoclonal) (M02)

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BACKGROUND

The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

REFERENCES

Zhang, Y., et al. Biochem. J. 427(3):499-511(2010) Beagle, B., et al. PLoS ONE 5 (7), E11821 (2010) : Arce, L., et al. BMC Cancer 9, 159 (2009) : Zhang, X., et al. J. Neurosci. Res. 86(11):2423-2431(2008) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :