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AES Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP14115b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14115b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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AES Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | Q08117 |
| Other Accession | NP_001121.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 21970 Da |
AES Antibody (C-term) - Additional info | |
| Gene ID 166 | |
| Other Names AES; GRG; Amino-terminal enhancer of split; Gp130-associated protein GAM; Protein ESP1; Protein GRG | |
| Target/Specificity This AES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-184 amino acids from the C-terminal region of human AES. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AES Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AES Antibody (C-term) - Protein Information | |
| Name AES | |
| Synonyms GRG | |
| Function Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state | |
| Cellular Location Nucleus (By similarity). | |
| Tissue Location Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver | |
AES Antibody (C-term) - Related products
AP14115b: AES Antibody (C-term)
AES Antibody (C-term) - Application data
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Western blot analysis of AES (arrow) using rabbit polyclonal AES Antibody (C-term) (Cat. #AP14115b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AES gene.
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AES Antibody (C-term) (Cat. #AP14115b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the AES antibody detected the AES protein (arrow).
AES Antibody (C-term) - Research Areas
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BACKGROUND
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
REFERENCES
Zhang, Y., et al. Biochem. J. 427(3):499-511(2010) Beagle, B., et al. PLoS ONE 5 (7), E11821 (2010) : Arce, L., et al. BMC Cancer 9, 159 (2009) : Zhang, X., et al. J. Neurosci. Res. 86(11):2423-2431(2008) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :