|Application ||WB, IHC-P, E|
|Calculated MW||69279 Da|
|Antigen Region||533-562 aa|
|Other Names||Homeodomain-interacting protein kinase 4, Hipk4, Gm162|
|Target/Specificity||This Mouse Hipk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 533-562 amino acids from the C-terminal region of mouse Hipk4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Hipk4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein kinase that phosphorylates murine TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. May act as a corepressor of transcription factors (Potential).|
|Tissue Location||Expressed at moderate levels in lung and white adipose tissues and weakly in brain and liver|
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Provided below are standard protocols that you may find useful for product applications.
Protein kinase that phosphorylates murine TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. It may act as a corepressor of transcription factors (Potential).
Arai, S., et al. FEBS Lett. 581(29):5649-5657(2007)
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
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