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WNT3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - WNT3 Antibody (Center) AP14130c
    WNT3 Antibody (Center) (Cat. #AP14130c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the WNT3 antibody detected the WNT3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P56703
Other Accession P17553, P31285, P27467, P56704, Q2LMP1, NP_110380.1
Reactivity Human
Predicted Chicken, Mouse, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39645 Da
Antigen Region 155-184 aa
Additional Information
Gene ID 7473
Other Names Proto-oncogene Wnt-3, Proto-oncogene Int-4 homolog, WNT3, INT4
Target/Specificity This WNT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-184 amino acids from the Central region of human WNT3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWNT3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WNT3
Synonyms INT4
Function Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
Citations (0)

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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.


Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Memarian, A., et al. Leuk. Lymphoma 50(12):2061-2070(2009)

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$ 295.00
$ 99.00
Cat# AP14130c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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