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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Map2k5 Antibody (C-term)   

Mouse Map2k5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Map2k5 Antibody (C-term) AP14154b
    Mouse Map2k5 Antibody (C-term) (Cat. #AP14154b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Map2k5 antibody detected the Map2k5 protein (arrow).
  • WB - Mouse Map2k5 Antibody (C-term) AP14154b
    Western blot analysis of Map2k5 (arrow) using rabbit polyclonal Mouse Map2k5 Antibody (C-term) (Cat. #AP14154b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Map2k5 gene.
  • WB - Mouse Map2k5 Antibody (C-term) AP14154b
    Mouse Map2k5 Antibody (C-term) (Cat. #AP14154b) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Map2k5 antibody detected the Map2k5 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9WVS7
Other Accession Q62862, Q13163, NP_035970.1
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50105 Da
Antigen Region 385-412 aa
Additional Information
Gene ID 23938
Other Names Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, Map2k5, Mek5, Mkk5, Prkmk5
Target/Specificity This Mouse Map2k5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-412 amino acids from the C-terminal region of mouse Map2k5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Map2k5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Map2k5
Synonyms Mek5, Mkk5, Prkmk5
Function Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Background

Map2k5 acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.

References

Spiering, D., et al. J. Biol. Chem. 284(37):24972-24980(2009)
Carter, E.J., et al. J. Cell. Sci. 122 (PT 17), 3104-3112 (2009) :
Sohn, S.J., et al. EMBO J. 27(13):1896-1906(2008)
Shishido, T., et al. Circ. Res. 102(11):1416-1425(2008)
Nakamura, K., et al. Mol. Cell. Biol. 27(12):4566-4577(2007)

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$ 295.00
$ 99.00
Cat# AP14154b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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