Mouse Mlk4 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q8VDG6 |
Other Accession | NP_663583.2 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 110112 Da |
Antigen Region | 566-593 aa |
Gene ID | 234878 |
---|---|
Other Names | Mitogen-activated protein kinase kinase kinase MLK4, Mixed lineage kinase 4, Mlk4, Kiaa1804 |
Target/Specificity | This Mouse Mlk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 566-593 amino acids from the Central region of mouse Mlk4. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Mouse Mlk4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Map3k21 |
---|---|
Synonyms | Kiaa1804, Mlk4 |
Function | Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mlk4 activates the JUN N-terminal pathway (By similarity).
References
Katayama, S., et al. Science 309(5740):1564-1566(2005)
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