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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   K Cadherin (CDH6) Antibody (C-term)   

K Cadherin (CDH6) Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - K Cadherin (CDH6) Antibody (C-term) AP1415b
    Western blot analysis of anti-DH6 Antibody (C-term) (RB14082) in 293 cell line lysates (35ug/lane). DH6(arrow) was detected using the purified Pab.
  • IHC-P - K Cadherin (CDH6) Antibody (C-term) AP1415b
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CDH6 antibody (C-term) (Cat.#AP1415b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - K Cadherin (CDH6) Antibody (C-term) AP1415b
    Flow cytometric analysis of NCI-H292 cells using CDH6 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55285
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 88309 Da
Antigen Region 665-695 aa
Additional Information
Gene ID 1004
Other Names Cadherin-6, Kidney cadherin, K-cadherin, CDH6
Target/Specificity This K Cadherin (CDH6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human K Cadherin (CDH6).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsK Cadherin (CDH6) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDH6
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression Also expressed in certain liver and kidney carcinomas
Research Areas
Citations (0)

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CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.


Liu,T., J. Proteome Res. 4 (6), 2070-2080 (2005)
Shimoyama,Y., Biochem. J. 349 (PT 1), 159-167 (2000)
Shimoyama,Y., J. Biol. Chem. 274 (17), 11987-11994 (1999)

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$ 295.00
$ 99.00
Cat# AP1415b
(40 western blots)
Availability: In Stock
Bulk Size
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