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GNAQ Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GNAQ Antibody (N-term) AP14179a
    GNAQ Antibody (N-term) (Cat. #AP14179a) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the GNAQ antibody detected the GNAQ protein (arrow).
  • WB - GNAQ Antibody (N-term) AP14179a
    Western blot analysis of GNAQ (arrow) using rabbit polyclonal GNAQ Antibody (N-term) (Cat. #AP14179a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GNAQ gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50148
Other Accession P38410, P82471, Q2PKF4, P21279, NP_002063.2
Reactivity Human
Predicted Mouse, Pig, Rat, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42142 Da
Antigen Region 52-78 aa
Additional Information
Gene ID 2776
Other Names Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q, GNAQ, GAQ
Target/Specificity This GNAQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human GNAQ.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGNAQ Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GAQ
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
Cellular Location Nucleus. Membrane. Nucleus membrane. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
Tissue Location Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level).
Research Areas
Citations (0)

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This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.


Dratviman-Storobinsky, O., et al. Invest. Ophthalmol. Vis. Sci. 51(12):6180-6182(2010)
Crouthamel, M., et al. Mol. Pharmacol. 78(4):767-777(2010)
Chillar, A., et al. Biochemistry 49(30):6365-6374(2010)
Klenke, S., et al. Pharmacogenet. Genomics 20(8):476-484(2010)
Salmanian, S., et al. Biochem. Biophys. Res. Commun. 395(4):577-582(2010)

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$ 295.00
$ 99.00
Cat# AP14179a
(40 western blots)
Availability: In Stock
Bulk Size
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