|Application ||WB, IHC-P, E|
|Other Accession||P04259, NP_775109.2|
|Calculated MW||60025 Da|
|Antigen Region||135-164 aa|
|Other Names||Keratin, type II cytoskeletal 6C, Cytokeratin-6C, CK-6C, Cytokeratin-6E, CK-6E, Keratin K6h, Keratin-6C, K6C, Type-II keratin Kb12, KRT6C, KRT6E|
|Target/Specificity||This KRT6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human KRT6C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KRT6C Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq].
Bowden, P.E. J. Invest. Dermatol. 130(2):336-338(2010)
Wilson, N.J., et al. J. Invest. Dermatol. 130(2):425-429(2010)
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Scherer, S.E., et al. Nature 440(7082):346-351(2006)
Hesse, M., et al. J. Cell. Sci. 114 (PT 14), 2569-2575 (2001) :
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