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CYTH1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CYTH1 Antibody (N-term) AP14202a
    CYTH1 Antibody (N-term) (Cat. #AP14202a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CYTH1 antibody detected the CYTH1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15438
Other Accession P97694, Q9QX11, NP_004753.1, NP_059430.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46413 Da
Antigen Region 37-65 aa
Additional Information
Gene ID 9267
Other Names Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1
Target/Specificity This CYTH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human CYTH1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCYTH1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYTH1
Synonyms D17S811E, PSCD1
Function Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.
Cellular Location Cell membrane; Peripheral membrane protein Cytoplasm, cytosol
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2.


El Azreq, M.A., et al. J. Immunol. 184(2):637-649(2010)
Quast, T., et al. Blood 113(23):5801-5810(2009)
Sendide, K., et al. J. Immunol. 174(7):4210-4219(2005)
Boehm, T., et al. EMBO J. 22(5):1014-1024(2003)
Mansour, M., et al. J. Biol. Chem. 277(35):32302-32309(2002)

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$ 295.00
$ 99.00
Cat# AP14202a
(40 western blots)
Availability: In Stock
Bulk Size
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