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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PRSS8 Antibody (Center)   

PRSS8 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRSS8 Antibody (Center) AP14207c
    PRSS8 Antibody (Center) (Cat. #AP14207c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PRSS8 antibody detected the PRSS8 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16651
Other Accession NP_002764.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36431 Da
Antigen Region 190-219 aa
Additional Information
Gene ID 5652
Other Names Prostasin, 3421-, Channel-activating protease 1, CAP1, Serine protease 8, Prostasin light chain, Prostasin heavy chain, PRSS8
Target/Specificity This PRSS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human PRSS8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRSS8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRSS8
Function Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Cellular Location Prostasin: Cell membrane; Single-pass membrane protein Prostasin heavy chain: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus
Tissue Location Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid
Research Areas
Citations (0)

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This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.


Chen, Y.W., et al. J. Biol. Chem. 285(41):31755-31762(2010)
Chen, M., et al. Mol. Cell. Biochem. 337 (1-2), 259-266 (2010) :
Fu, Y.Y., et al. Hum. Reprod. 25(3):623-632(2010)
Ko, T., et al. J. Biomed. Biotechnol. 2010, 793843 (2010) :
Chang, J.H., et al. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 31(6):712-719(2009)

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$ 295.00
$ 99.00
Cat# AP14207c
(40 western blots)
Availability: In Stock
Bulk Size
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