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>   home   >   Products   >   Primary Antibodies   >   MCPH1 Antibody (N-term)   

MCPH1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MCPH1 Antibody (N-term) AP14216a
    MCPH1 Antibody (N-term) (Cat. #AP14216a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MCPH1 antibody detected the MCPH1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NEM0
Other Accession Q5IFK1, NP_078872.2, NP_001166045.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 92877 Da
Antigen Region 104-133 aa
Additional Information
Gene ID 79648
Other Names Microcephalin, MCPH1
Target/Specificity This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human MCPH1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMCPH1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MCPH1
Function Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Tissue Location Expressed in fetal brain, liver and kidney.
Citations (0)

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This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.


Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Wang, Y.Q., et al. Hum. Mol. Genet. 13(11):1131-1137(2004)

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$ 295.00
$ 99.00
Cat# AP14216a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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