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DRAGON (RGMB) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DRAGON (RGMB) Antibody (C-term) AP1421b
    All lanes : Anti-DRAGON (RGMB) Antibody (C-term) at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: mouse brain lysate Lane 3: mouse cerebellum lysate Lane 4: NCI-H460 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - DRAGON (RGMB) Antibody (C-term) AP1421b
    Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with DRAGON (RGMB) (C-term) (Cat.#AP1421b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • WB - DRAGON (RGMB) Antibody (C-term) AP1421b
    Western blot analysis of DRAGON (RGMB) Antibody (C-term) in K562 cell line lysates (35ug/lane). DRAGON (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6NW40
Other Accession Q7TQ33
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47547 Da
Antigen Region 376-406 aa
Additional Information
Gene ID 285704
Other Names RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB
Target/Specificity This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-406 amino acids from the C-terminal region of human DRAGON (RGMB).
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDRAGON (RGMB) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft
Research Areas
Citations (0)

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Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.


Schnichels,S., Gene Expr. Patterns 8 (1), 1-11 (2007)
Metzger,M., Dev. Dyn. 234 (1), 169-175 (2005)
Xia,Y., Endocrinology 146 (8), 3614-3621 (2005)

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$ 295.00
$ 99.00
Cat# AP1421b
(40 western blots)
Availability: In Stock
Bulk Size
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