|Application ||WB, IHC-P, E|
|Calculated MW||41267 Da|
|Antigen Region||213-242 aa|
|Other Names||SLC2A4 regulator, GLUT4 enhancer factor, GEF, Huntington disease gene regulatory region-binding protein 1, HDBP-1, SLC2A4RG, HDBP1|
|Target/Specificity||This HDBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-242 amino acids from the Central region of human HDBP1.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HDBP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.|
|Cellular Location||Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus|
|Tissue Location||According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
THDBP1 is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. This protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene.
Jones,M.R., Fertil. Steril. (2008)
McGee,S.L., FASEB J. 20 (2), 348-349 (2006)
Tanaka,K., J. Biol. Chem. 279 (8), 7275-7286 (2004)
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