|Application ||WB, E|
|Other Accession||Q95KI4, NP_071434.2|
|Calculated MW||39513 Da|
|Antigen Region||37-65 aa|
|Other Names||Modulator of apoptosis 1, MAP-1, MAP1, Paraneoplastic antigen Ma4, MOAP1, PNMA4|
|Target/Specificity||This MOAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human MOAP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MOAP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.|
|Tissue Location||Widely expressed, with high levels in heart and brain.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.
Lee, S.S., et al. Exp. Cell Res. 315(7):1313-1325(2009)
Foley, C.J., et al. Mol. Cell. Biol. 28(14):4520-4535(2008)
Fu, N.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 104(24):10051-10056(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Vos, M.D., et al. J. Biol. Chem. 281(8):4557-4563(2006)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.