|Application ||WB, E|
|Calculated MW||52989 Da|
|Antigen Region||445-474 aa|
|Other Names||TOM1-like protein 1, Src-activating and signaling molecule protein, Target of Myb-like protein 1, TOM1L1, SRCASM|
|Target/Specificity||This TOM1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human TOM1L1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TOM1L1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).|
|Cellular Location||Golgi apparatus, Golgi stack. Endosome membrane. Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Note=A small proportion is membrane-associated.|
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Provided below are standard protocols that you may find useful for product applications.
Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).
Qi, Y., et al. Anticancer Res. 30(9):3535-3539(2010)
Liu, N.S., et al. EMBO J. 28(22):3485-3499(2009)
Meulener, M.C., et al. J. Cutan. Pathol. 36(3):291-295(2009)
Elmarghani, A., et al. Mediators Inflamm. 2009, 416298 (2009) :
Thalappilly, S., et al. Proteomics 8(15):3071-3081(2008)
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