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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   L3MBTL2 Antibody (C-term)   

L3MBTL2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - L3MBTL2 Antibody (C-term) AP14235b
    L3MBTL2 Antibody (C-term) (Cat. #AP14235b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the L3MBTL2 antibody detected the L3MBTL2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q969R5
Other Accession NP_113676.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 79110 Da
Antigen Region 627-656 aa
Additional Information
Gene ID 83746
Other Names Lethal(3)malignant brain tumor-like protein 2, H-l(3)mbt-like protein 2, L(3)mbt-like protein 2, L3MBTL2
Target/Specificity This L3MBTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 627-656 amino acids from the C-terminal region of human L3MBTL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsL3MBTL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name L3MBTL2
Function Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

References

Guo, Y., et al. Nucleic Acids Res. 37(7):2204-2210(2009)
Lechtenberg, B.C., et al. Protein Sci. 18(3):657-661(2009)
Trojer, P., et al. Cell 129(5):915-928(2007)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Ogawa, H., et al. Science 296(5570):1132-1136(2002)

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$ 295.00
$ 99.00
Cat# AP14235b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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