|Application ||IHC-P, E|
|Calculated MW||40044 Da|
|Antigen Region||36-65 aa|
|Other Names||LIM/homeobox protein Lhx6, LIM homeobox protein 6, LIM/homeobox protein Lhx61, Lhx6, Lhx61|
|Target/Specificity||This Lhx6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids of mouse Lhx6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Lhx6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.|
|Tissue Location||Brain specific. Expressed by neurons in the amygdala that are activated by reproductive olfactory stimuli and project in regions of the hypothalamus involved in reproduction (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Lhx6 is a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. This protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells.
Lopez-Bendito,G., J. Neurosci. 28 (7), 1613-1624 (2008)
Ko,S.O., Dev. Biol. 312 (1), 435-447 (2007)
Jepsen,K., Nature 450 (7168), 415-419 (2007)
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