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CCDC50 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CCDC50 Antibody (Center) AP14241C
    CCDC50 Antibody (Center) (Cat. #AP14241c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CCDC50 antibody detected the CCDC50 protein (arrow).
  • IHC-P - CCDC50 Antibody (Center) AP14241C
    CCDC50 Antibody (Center) (AP14241c)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCDC50 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IVM0
Other Accession Q810U0, Q810U5, NP_777568.1, NP_848018.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35822 Da
Antigen Region 86-114 aa
Additional Information
Gene ID 152137
Other Names Coiled-coil domain-containing protein 50, Protein Ymer, CCDC50, C3orf6
Target/Specificity This CCDC50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human CCDC50.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCDC50 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCDC50
Synonyms C3orf6
Function Involved in EGFR signaling.
Cellular Location Cytoplasm. Note=Associated with microtubules of the cytoskeleton and mitotic apparatus.
Tissue Location Isoform 1 and isoform 2 are coexpressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart
Citations (0)

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This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].


Farfsing, A., et al. Leukemia 23(11):2018-2026(2009)
Kameda, H., et al. Biochem. Biophys. Res. Commun. 378(4):744-749(2009)
Bohgaki, M., et al. Biochim. Biophys. Acta 1783(5):826-837(2008)
Modamio-Hoybjor, S., et al. Am. J. Hum. Genet. 80(6):1076-1089(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 295.00
$ 99.00
Cat# AP14241C
(40 western blots)
Availability: In Stock
Bulk Size
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