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AGGF1 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP14242a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14242a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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AGGF1 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | Q8N302 |
| Other Accession | NP_060516.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 80977 Da |
AGGF1 Antibody (N-term) - Additional info | |
| Gene ID 55109 | |
| Other Names AGGF1; GPATC7; GPATCH7; VG5Q; Angiogenic factor with G patch and FHA domains 1; Angiogenic factor VG5Q; G patch domain-containing protein 7; Vasculogenesis gene on 5q protein | |
| Target/Specificity This AGGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-90 amino acids from the N-terminal region of human AGGF1. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AGGF1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AGGF1 Antibody (N-term) - Protein Information | |
| Name AGGF1 | |
| Synonyms GPATC7, GPATCH7, VG5Q | |
| Function Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion | |
| Cellular Location Cytoplasm. Secreted. Note=Cytoplasmic in microvascular endothelial cells. Upon angiogenesis, when endothelial cell tube formation is initiated, it is secreted | |
| Tissue Location Widely expressed. Expressed in endothelial cells, vascular smooth muscle cells and osteoblasts. Expressed in umbilical vein endothelial cells and microvascular endothelial cells | |
AGGF1 Antibody (N-term) - Related products
AGGF1 Antibody (N-term) - Application data
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AGGF1 Antibody (N-term) (Cat. #AP14242a) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AGGF1 antibody detected the AGGF1 protein (arrow).
AGGF1 Antibody (N-term) - Research Areas
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BACKGROUND
This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.
REFERENCES
Fan, C., et al. J. Biol. Chem. 284(35):23331-23343(2009) Hu, Y., et al. Ann. Hum. Genet. 72 (PT 5), 636-643 (2008) : Gutierrez, S., et al. Am. J. Med. Genet. A 140(24):2832-2833(2006) Olsen, J.V., et al. Cell 127(3):635-648(2006) Kihiczak, G.G., et al. Int. J. Dermatol. 45(8):883-890(2006)
