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CIAO1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CIAO1 Antibody (Center) AP14244c
    CIAO1 Antibody (Center) (Cat. #AP14244c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CIAO1 antibody detected the CIAO1 protein (arrow).
  • IHC-P - CIAO1 Antibody (Center) AP14244c
    CIAO1 Antibody (Center) (AP14244c)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CIAO1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O76071
Other Accession Q32PJ6, NP_004795.1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37840 Da
Antigen Region 155-183 aa
Additional Information
Gene ID 9391
Other Names Probable cytosolic iron-sulfur protein assembly protein CIAO1 {ECO:0000255|HAMAP-Rule:MF_03037}, WD repeat-containing protein 39 {ECO:0000255|HAMAP-Rule:MF_03037}, CIAO1 {ECO:0000255|HAMAP-Rule:MF_03037}, WDR39
Target/Specificity This CIAO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the Central region of human CIAO1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCIAO1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CIAO1 {ECO:0000255|HAMAP-Rule:MF_03037}
Synonyms WDR39
Function Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Citations (0)

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CIAO1 is an essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1.


Srinivasan, V., et al. Structure 15(10):1246-1257(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)
Johnstone, R.W., et al. J. Biol. Chem. 273(18):10880-10887(1998)

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$ 295.00
$ 99.00
Cat# AP14244c
(40 western blots)
Availability: In Stock
Bulk Size
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