|Application ||WB, E|
|Other Accession||P16067, NP_776149.1|
|Calculated MW||117060 Da|
|Antigen Region||480-509 aa|
|Other Names||Atrial natriuretic peptide receptor 2, Atrial natriuretic peptide receptor type B, ANP-B, ANPR-B, NPR-B, Guanylate cyclase B, GC-B, Npr2|
|Target/Specificity||This Mouse Npr2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-509 amino acids from the Central region of mouse Npr2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Npr2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Widely expressed. Expressed in the columnar proliferating and prehypertrophic chondrocyte layers of the tibia|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.
Zhang, M., et al. Science 330(6002):366-369(2010)
Sogawa, C., et al. Am. J. Pathol. 177(2):822-828(2010)
Zhao, Z., et al. Proc. Natl. Acad. Sci. U.S.A. 106(42):18016-18021(2009)
Schmidt, H., et al. Proc. Natl. Acad. Sci. U.S.A. 106(39):16847-16852(2009)
Yoder, A.R., et al. Peptides 29(9):1575-1581(2008)
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