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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Mouse TRPV3 Antibody (N-term)   

Mouse TRPV3 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse TRPV3 Antibody (N-term) AP1425a
    Anti-TRPV3 (N-term) at 1:1000 dilution + mouse heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 91kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - Mouse TRPV3 Antibody (N-term) AP1425a
    Formalin-fixed and paraffin-embedded human testis tissue reacted with TRPV3 Antibody (N-term) (Cat.#AP1425a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8K424
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 90663 Da
Antigen Region 90-119 aa
Additional Information
Gene ID 246788
Other Names Transient receptor potential cation channel subfamily V member 3, TrpV3, Trpv3
Target/Specificity This Mouse TRPV3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of mouse TRPV3.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse TRPV3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Trpv3
Function Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen) (By similarity).
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Expressed in keratinocytes and hair follicles.
Research Areas
Citations (0)

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TRPV3 belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels.


Frederick,J., Biochem. Biophys. Res. Commun. 358 (4), 1058-1064 (2007)
Asakawa,M., J. Invest. Dermatol. 126 (12), 2664-2672 (2006)

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$ 295.00
$ 99.00
Cat# AP1425a
(40 western blots)
Availability: In Stock
Bulk Size
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