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Mouse Plk5 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Plk5 Antibody (N-term) AP14276a
    Mouse Plk5 Antibody (N-term) (Cat. #AP14276a) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Plk5 antibody detected the Plk5 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q4FZD7
Other Accession NP_898975.2
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 66055 Da
Antigen Region 4-31 aa
Additional Information
Gene ID 216166
Other Names Inactive serine/threonine-protein kinase PLK5, Polo-like kinase 5, PLK-5, Plk5 {ECO:0000250|UniProtKB:Q64702}
Target/Specificity This Mouse Plk5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-31 amino acids from the N-terminal region of mouse Plk5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Plk5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Plk5 {ECO:0000250|UniProtKB:Q64702}
Function Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.
Cellular Location Nucleus, nucleolus. Cytoplasm
Tissue Location Expressed in the cerebellum, eye and brain cortex (at protein level). Expressed in highly differentiated tissues, such as brain, eyes and ovary. Not detectable in proliferating tissues, such as the colon, spleen and placenta
Research Areas
Citations (0)
citation

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Background

PLK5 (Serine/threonine-protein kinase PLK5) belongs to the protein kinase superfamily and Ser/Thr protein kinase family and CDC5/Polo subfamily. PLK5P contains 1 POLO box domain and 1 Serine/Threonine protein kinase catalytic domain.

References

Pereira, J.D., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15957-15962(2010)
Andrysik, Z., et al. Nucleic Acids Res. 38(9):2931-2943(2010)
Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004) :

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$ 365.00
$ 140.00
Cat# AP14276a
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